Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.
The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research
Aug 10th, 2020: Milou’s and Yannick’s paper on the C. elegans oscillator now out in Mol Syst Biol. Check here for a brief summary. Apr 30th, 2020: Congratulations, Dr. Yannick Hauser, on a successful defense via video conferencing! Mar 30th, 2020: Chiara’s and Florian’s work on temporal coordination of juvenile-to-adult transition in the worm now… Continue reading Lab news
2020 Meuse, M.W.M.#, Hauser, Y.P.#, Morales Moreno, L.J., Hendriks, G.-J., Eglinger, J., Bogaarts, G., Tsiairis, C., Großhans, H.* (2020) Developmental function and state transitions of a gene expression oscillator in C. elegans. Mol Syst Biol. 16: e9498 (# equal contribution) Azzi, C.#, Aeschimann, F.#, Neagu, A., Großhans, H.* (2020) A branched heterochronic pathway directs juvenile-to-adult… Continue reading Publications