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Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.

Research

The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research

Lab news

Sept 25th, 2020: Applications for position of a Junior Group Leader (Tenure Track) in Multicellular Systems now open at FMI Sept 10th, 2020: Congratulations, Milou, for winning the Edmond H Fischer Prize for the best PhD Thesis defended at FMI in 2019! Aug 10th, 2020: Milou’s and Yannick’s paper on the C. elegans oscillator now… Continue reading Lab news

Publications

2020 Meuse, M.W.M.#, Hauser, Y.P.#, Morales Moreno, L.J., Hendriks, G.-J., Eglinger, J., Bogaarts, G., Tsiairis, C., Großhans, H.* (2020) Developmental function and state transitions of a gene expression oscillator in C. elegans. Mol Syst Biol. 16: e9498 (# equal contribution) Azzi, C.#, Aeschimann, F.#, Neagu, A., Großhans, H.* (2020) A branched heterochronic pathway directs juvenile-to-adult… Continue reading Publications