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Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.

Research

The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research

Lab news

Jan 9th, 2019: Welcome to our new trainee, Carolin! Jan 6th, 2019: The paper on timing differentiation into a sexually dimorphic nervous system is now out in eLife along with a preview article. Dec 19th, 2018: Farewell to Sarah and Giovanna! We wish you a great start in your new positions! Nov 28th, 2018: Congratulations, Ben,… Continue reading Lab news

Publications

2019 Pereira, L., Aeschimann, F., Wang, C., Lawson, H., Serrano-Saiz, E., Portman, D.S., Großhans, H., Hobert, O. (2019) Timing mechanism of sexually dimorphic nervous system differentiation. eLIFE 8: e42078.(Preview: Perry & Desplan (2019) eLIFE 8: e41523.) 2018 Kumari, P.#, Aeschimann, F.#, Gaidatzis, D.#, Keusch, J.J.#, Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H.*,… Continue reading Publications