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Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study developmental clocks and timers as well as RNA silencing pathways. Read more here.
Research
The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research
Lab news
Apr 28, 2023: Congratulations, Maike, on your successful Phd Thesis Defense! Apr 21, 2023: Check our new preprint on how TRIM71/LIN-41 functions through the miRISC core component TNRC6/GW182 – and a Tweet putting the results in context. Sep 6, 2022: Congratulations, Stephen, for obtaining an Ambizione Grant from SNSF that will allow you to pursue… Continue reading Lab news
Publications
2023 Welte, T.*, Goulois, A., Stadler, M.B., Hess, D., Soneson, C., Neagu, A., Azzi, C., Lübke, M.J., Seebacher, J., Schmidt, I., Estoppey, D., Nigsch, F., Reece-Hoyes, J., Hoepfner, D, Großhans, H.* (2023) Convergence of multiple RNA-silencing pathways on GW182/TNRC6. bioRxiv Preprint doi: 10.1101/2023.04.20.537632 Meeuse, M.W.M., Hauser, Y.P., Nahar, S., Smith, A.A.T.S., Braun, K., Azzi, C.,… Continue reading Publications
Grosshans Lab 