Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.
The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research
Apr 8th, 2019: Closing date for applications to the International PhD Program of the FMI approaching fast (May 1st) – find details on how to apply here. Mar 25th, 2019: Our paper on how to control the onset of juvenile-to-adult transition now out – see a summary here and the paper here Mar 15th, 2019:… Continue reading Lab news
2019 Aeschimann, F., Neagu, A., Rausch, M., and Großhans, H. (2019). A single let-7 target to coordinate transition to adulthood. Life Science Alliance 2, e201900335. Pereira, L., Aeschimann, F., Wang, C., Lawson, H., Serrano-Saiz, E., Portman, D.S., Großhans, H., Hobert, O. (2019) Timing mechanism of sexually dimorphic nervous system differentiation. eLIFE 8: e42078.(Preview: Perry & Desplan… Continue reading Publications