Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.
The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research
Apr 20th, 2018: Florian’s collaborative work with Rafal Ciosk’s lab reveals an unusual mode of RNA recognition by LIN41/TRIM71 – summarized here and detailed here. Apr 14th, 2018: Closing date for applications to the International PhD Program of the FMI approaching fast (May 1st) – find details and apply here. Mar 21st, 2018: Giovanna’s work on… Continue reading Lab news
2018 Kumari, P.#, Aeschimann, F.#, Gaidatzis, D.#, Keusch, J.J.#, Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H.*, Großhans, H., Ciosk, R.* (2018) Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. Nat. Commun. 9: 1549 (# equal contribution) Brancati, G., and Großhans, H.* (2018). An interplay of miRNA abundance and… Continue reading Publications