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Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.

Research

The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research

Lab news

Apr 30th, 2020: Congratulations, Dr. Yannick Hauser, on a successful defense via video conferencing! Mar 30th, 2020: Chiara’s and Florian’s work on temporal coordination of juvenile-to-adult transition in the worm now out here. Dec 13th, 2019: Congratulations, Dr. Milou Meeuse, on a successful defense! Oct 14th, 2019: Welcome to our two new PhD students, Marit… Continue reading Lab news

Publications

2020 Azzi, C.#, Aeschimann, F.#, Neagu, A., Großhans, H.* (2020) A branched heterochronic pathway directs juvenile-to-adult transition through two LIN-29 isoforms. eLIFE. 9: e53387. (# equal contribution) 2019 Welte, T.#,*, Tuck, A.C.#, Papasaikas, P., Carl, S.H., Flemr, M., Knuckles, P., Rankova, A., Bühler, M., and Großhans H.* (2019) The RNA hairpin binder TRIM71 modulates alternative… Continue reading Publications