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Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.

Research

The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research

Lab news

Nov 5th, 2018: How to time initiation of adulthood – read our pre-print Oct 1st, 2018: Welcome to our new PhD student Maike! Sep 19th, 2018: How to time differentiation into a sexually dimorphic nervous system – read the pre-print of our fun collaboration with the Hobert lab here. Aug 31st, 2018: Farewell to Florian! We wish… Continue reading Lab news

Publications

2018 Kumari, P.#, Aeschimann, F.#, Gaidatzis, D.#, Keusch, J.J.#, Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H.*, Großhans, H., Ciosk, R.* (2018) Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. Nat. Commun. 9: 1549 (# equal contribution) Brancati, G., and Großhans, H.* (2018). An interplay of miRNA abundance and… Continue reading Publications