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Welcome to the Großhans Lab at FMI. We use C. elegans and mammalian cells to study mechanisms and function of oscillatory gene expression, cell fate control mechanisms, and microRNAs. Read more here.

Research

The lab is interested in understanding the molecular and physiological functions of mechanisms that regulate gene expression. Our current major interests are linked to the three areas described in more detail below, namely Oscillatory Gene Expression, Cell Fate Control, and MicroRNAs. However, we are happy to let the data guide us and have thus also… Continue reading Research

Lab news

Aug 15th, 2018: Together with the group of Dr. Marc Bühler and in the context of the NCCR RNA & Disease, we have a position in bioinformatics/quantitative biology available – find details and a link to apply online here. May 29th, 2018: Giovanna’s paper is collecting recommendations on F1000Prime: doi:10.3410/f.733028808.793544522 and doi:10.3410/f.733028808.793546212 May 24th, 2018: Join us for Helge’s… Continue reading Lab news

Publications

2018 Kumari, P.#, Aeschimann, F.#, Gaidatzis, D.#, Keusch, J.J.#, Ghosh, P., Neagu, A., Pachulska-Wieczorek, K., Bujnicki, J.M., Gut, H.*, Großhans, H., Ciosk, R.* (2018) Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition. Nat. Commun. 9: 1549 (# equal contribution) Brancati, G., and Großhans, H.* (2018). An interplay of miRNA abundance and… Continue reading Publications