Stephen wants to understand how animals can achieve and restrict dynamic changes to chromatin during development, and specifically which factors are necessary to coordinate changes over time and how cell identity is maintained. He therefore aims to study how disruptions of these processes affect animals. This work is particularly important, as very little is known about the dynamics of chromatin in living animals, yet perturbations to these systems are associated with many diseases such as cancer and aging.
Stephen is planning to recruit a PhD student during the current FMI PhD admission round and is setting up some collaborations to advance his project.
Grosshans Lab 