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Research on developmental timing, cell fates and RNA

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Paper

OUT NOW our preprint titled “Two parallel arms of the heterochronic pathway direct coordinated juvenile-to-adult transition through distinct LIN-29 isoforms”

September 27, 2019April 5, 2024 grosshanslab

If you prefer a linear mode of timing development, look at this preprint of Chiara’s and Florian’s work: how to coordinate events that take place during worm ‘puberty’.

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Paper

OUT NOW our preprint titled “Developmental function and state transitions of a gene expression oscillator in C. elegans”

September 5, 2019April 5, 2024 grosshanslab

Gene expression oscillators can structure biological events temporally and spatially. Want to know more about it? Then read our preprint available on bioRxiv!

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People

Welcome to our new PhD student, Saheli!

September 2, 2019April 5, 2024 grosshanslab

Saheli holds a Master’s degree in neurogenetics. For her thesis, she worked on the role of circadian clock cells in maintaining sleep homeostasis in Drosophila melanogaster

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Paper

OUT NOW our collaboration with the Bühler lab titled ” The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1″

August 5, 2019April 5, 2024 grosshanslab

TRIM71/LIN-41 is a phylogenetically conserved regulator of development that controls stem cell fates. In Thomas’s paper we show that TRIM71 primarily influences the gene expression of mouse embryonic stem cells (mESCs) through its RNA-binding ability. Read more on the FMI webpage

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Conferences

June 20-24, 2019 | 22nd International C. elegans conference | UCLA, Los Angeles

June 24, 2019April 5, 2024 grosshanslab
This year, the International C. elegans conference took place at the UCLA campus
Chiara was selected for a talk where she presented her PhD project, sharing some insights on the two parallel arms of the heterochronic pathway defined by LIN-29 isoforms
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