Maike discussed her project on the Spatiotemporal Organization of a Developmental Oscillator
Congratulations, Maike, on your successful Phd Thesis Defense!
Author: grosshanslab
OUT NOW our preprint titled “Convergence of multiple RNA-silencing pathways on GW182/TNRC6”
TRIM71/LIN-41 is a phylogenetically conserved RNA-binding protein that functions in mammalian stem cell reprogramming, brain development, and cancer. TRIM71 recognizes target mRNAs through hairpin motifs, however little is known about the silencing mechanism. Take a peek at Thomas’s work – available as a preprint at bioRxiv
Welcome to our new PhD student, Leonie!
Leonie obtained a French-German BSc in Human and Molecular Biology from the Universities of Saarbrücken and Strasbourg and a MSc in Molecular Biology and Genetics from the University of Strasbourg. During her master thesis at the IGBMC in Strasbourg she focused on understanding the role of BCL7 proteins in SWI/SNF assembly and function. She joined the Grosshans lab as a PhD student in March 2023, focusing on understanding the dynamics of heterochromatin during the development, using C. elegans developmental oscillations as a model.
Welcome to our new PostDoc, Michael!
Michael moved to Austria after high school to study Molecular Medicine at the Medical University of Innsbruck. While studying there, he created a platform for genome-wide CRISPR/Cas9-loss-of-function screens at the Institute for Developmental Immunology (Biocenter). In his PhD research, he used this technique to discover new regulators of miRNA biogenesis and their function. Fascinated by regulatory molecular mechanisms and the interaction between RNA molecules and proteins, he joined the Grosshans Lab in early 2023. Currently, he is researching how LIN-28 regulates its targets during C. elegans development, using methods like biochemistry, microscopy, and omics.
January 30th – February 1st, 2023 | NCCR RNA &Disease Annual Retreat | Kandersteg, Switzerland
Grosshans Lab 