Research on developmental timing, cell fates and RNA
miRNAs control target mRNAs by attaching to partially matching sequences, but some target RNAs can have the opposite effect. In TDMD (target-directed miRNA degradation), binding of miRNAs to RNAs with extensive complementarity leads to miRNA 3′-end tailing, trimming, and loss.
“This process functions in the test tube with fly lysates, but also in cells in which viral RNAs can direct host miRNAs for degradation”
Read more here
We wish you a smooth start in your new position as an Assistant Professor at the Institute of Bioorganic Chemistry Polish Academy of Science, Posnan!
The University of Basel (UB) and the global headquarters of Novartis are very close to each other, just one kilometer apart on the banks of the Rhine. The key to their partnership, however, lies across the river at the Friedrich Miescher Institute for Biomedical Research (FMI), which is an independent institution with long-standing connections to both the university and the pharmaceutical giant. Read more here
Take a peek at Giovanna’s manuscript on miRNA specificity – available as a preprint on bioRxiv.
Read here about Sarah’s and Takashi’s views on how to achieve a productive wet lab–dry lab collaboration.
Grosshans Lab 