People

Welcome to our new PostDoc, Michael!

Michael moved to Austria after high school to study Molecular Medicine at the Medical University of Innsbruck. While studying there, he created a platform for genome-wide CRISPR/Cas9-loss-of-function screens at the Institute for Developmental Immunology (Biocenter). In his PhD research, he used this technique to discover new regulators of miRNA biogenesis and their function. Fascinated by regulatory molecular mechanisms and the interaction between RNA molecules and proteins, he joined the Grosshans Lab in early 2023. Currently, he is researching how LIN-28 regulates its targets during C. elegans development, using methods like biochemistry, microscopy, and omics.

People

Congratulations, Stephen for winning an SNSF Ambizione Grant!

Stephen wants to understand how animals can achieve and restrict dynamic changes to chromatin during development, and specifically which factors are necessary to coordinate changes over time and how cell identity is maintained. He therefore aims to study how disruptions of these processes affect animals. This work is particularly important, as very little is known about the dynamics of chromatin in living animals, yet perturbations to these systems are associated with many diseases such as cancer and aging.
Stephen is planning to recruit a PhD student during the current FMI PhD admission round and is setting up some collaborations to advance his project.

People

Welcome to our new PhD student, Simona!

Simona studied Pharmaceutical Chemistry at the University of Milan, Italy. For her Master Thesis, she researched the importance of metabolic rewiring during neuroblastoma differentiation in the Giovanni Galli Biochemistry and Molecular Biology of Metabolism Lab. Following her graduation in 2019, she worked as a research associate in the same lab, focusing on characterizing the role of a zing finger protein during white adipogenesis. In August 2022, she joined the Grosshans lab to explore protein degradation regulation during C. elegans development.